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Sylvain Moineau Ph.D.
Professeur titulaire

Département de biochimie, de microbiologie et de bio-informatique
Faculté des sciences et de génie
Pavillon Alexandre-Vachon
1045 avenue de la Médecine, Université Laval
Québec, Canada, G1V 0A6
Tel: 418 656-3712
Fax: 418 656-2861
Courriel: sylvain.moineau@bcm.ulaval.ca

Welcome on Sylvain Moineau's laboratory website

In our laboratory, we are studying bacteriophages (or phages).

It is now recognized that phages are the most abundant biological entities on the planet. These viruses specifically infect bacteria. They are found in the same enviroments as their bacterial hosts and play a key role in maintaining the balance of ecosystems. Phages are also excellent viral models applicable to various research areas.

Bacteriophages can be both friends and foes. Friends since they suppress bacterial populations with harmful properties, including pathogenic bacteria. These phages can have industrial and medical applications as biocontrol agents. Foes because they can destroy bacteria that play an important role in food fermentations.

Our main goal is to increase knowledge of phage biology. We favor an integrative approach (combining data from genomics, transcriptomics, proteomics, and structural biology) to understand the interactions between phages and bacteria. New tools are also developed to remove bacteriophages in dairy fermentations and to favor their use as antibacterial agents in various industrial sectors and public health.

To know more about our research projects, visit this website (In French): Research

Our laboratory also houses the largest public collection of bacteriophages in the world (www.phage.ulaval.ca).

Recent publications


Trudel, L., M. Frenette, S. Moineau. 2017. CRISPR–Cas in the laboratory classroom. Nature Microbiology 2:17018. Résumé

Hynes, A.P., M.-L. Lemay, L. Trudel, H. Deveau, M. Frenette, D.M. Tremblay et S. Moineau. 2017. Detecting natural adaptation of the Streptococcus thermophilus CRISPR-Cas systems in research and classroom settings. Nat. Protoc. Résumé

Moineau, S. et D.M. Tremblay. 2017. Bacteriophage. Reference Module in Life Sciences. Pages 1-5. doi:10.1016/B978-0-12-809633-8.06122-7. Résumé

Hamdi, S., G.M. Rousseau, S.J. Labrie, D.M. Tremblay, R. Saïed Kourda, K. Ben Slama et S. Moineau. 2017. Characterization of two polyvalent phages infecting Enterobacteriaceae. Sci. Rep. Résumé

Champagne, C.P., S. Moineau, S. Lafleur et T. Savard. 2017. The effect of bacteriophages on the acidification of a vegetable juice medium by microencapsulated Lactobacillus plantarum. Food Microbiol. 63:28-34. Résumé

Turgeon, N., K. Michel, T.-L. Ha, E. Robine, S. Moineau et C. Duchaine. 2016. Resistance of aerosolized bacterial viruses to four germicidal products. PloS one 11:e0168815 Résumé

Labrie, S.J. et S. Moineau. 2016. Phosphorylation, an altruistic bacterial trick to halt phages. Cell Host Microbe 20:409-410. Résumé

Melo, A. G., S. Labrie, J. Dumaresq, R. Roberts, D. Tremblay et S. Moineau. 2016. Complete genome sequence of Brevibacterium linens SMQ-1335. Genome Announc. 4:e01242-16. Résumé

Hamdi, S., G. Rousseau, S. Labrie, R.S. Kourda, D. Tremblay, S. Moineau, and K.B. Slama. 2016. Characterization of five Podoviridae phages infecting Citrobacter freundii. Front. Microbiol. 7.

Hynes, A.P., M.L. Lemay, and S. Moineau. 2016. Applications of CRISPR-Cas in its natural habitat. Curr. Opin. Chem. Biol. 34:30-36.

Hynes, A.P., S.J. Labrie, and S. Moineau. 2016. Programming Native CRISPR Arrays for the Generation of Targeted Immunity. mBio 7:e00202-16. Abstract

Tremblay-Bouliane, K., C. Olsen, D. Tremblay, S. Moineau, B. Gaillet and A. Garnier. 2016. Screening peptide-ore interactions with a phage display library for bio-flotation application. CIM Journal. 7:178-184.

See all the publications

March 2017

CHR - Researcher of the Month

Le Fil (In French)
From research to teaching

February 2017

NSERC John C. Polanyi Award

Video (English subtitles)


FSG - News (In French)

UL - Press release (In French)

The Globe and Mail

Le Soleil (In French)

Le Fil (In French)

CRISPR: Science Borealis Blog

December 2016

CRISPR: Gairdner Symposium

November 2016

Highly Cited Researcher 2016

October 2016

Le Fil (In French)

September 2016

Flavelle medal

Press release (In French)

Québec Science (In French)

August 2016

Magazine Contact (In French)

June 2016

Life Sciences in Québec

May 2016

Grands Diplômés 2016 (French)

Avril 2016

Bravo Denise !

FRQNT - CRISPR: Origin of the discovery (In French)

Bravo Marie-Laurence !

Bravo Hany !

March 2016

CRISPR: Assemblée nationale (In French)

CRISPR: Les années lumière (In French)


See all the news




(Dernière mise à jour, 6 March 2017)
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Réalisation: Équipe Tactic